The multi-lineage differentiation potential and highlyviable nature of stem cells has provided many potentialtechniques to treat various diseases. Clinically, MSCtransplantation has become one of the treatment options forfull-thickness articular cartilage defects, osteogenesisimperfecta and myocardial infarction, while applications toother diseases are being developed The advantages of MSCtransplantation over other cell transplantation therapies isbecause MSCs are easy to harvest, isolate and grow, withminimum involvement of in vitro techniques .