Many microbiology laboratories now require reliable routine phenotypic methods to detect methicillin-resistant Staphylococcus aureus (MRSA) in the absence of genotypic facilities. The mainstay is simplicity and cost effectiveness.The aim of this study was to evaluate the performance of various phenotypic methods to detect methicillin-resistant Staphylococcus aureus.The fifty S. aureus isolates tested in this study included 33 MRSA and 17 methicillin-sensitive S. aureus (MSSA) strains. All of the MRSA strains produced green colonies on MRSA ID and showed agglutination with the MRSA screen test.The cefoxitin disc diffusion test showed 100% sensitivity and 100% specificity, while the oxacillin disc diffusion test was not that accurate. On the other hand, there was no significant difference between Mueller-Hinton agar and Iso-sensitest agar.