Background: Fluid balance is an integral component of hemodialysis (HD) treatments to prevent under- or overhydration, both of which have been demonstrated to have significant effects on intradialytic morbidity and long-term cardiovascular complications. Fluid removal is usually achieved by ultrafiltration to achieve a clinically derived value for "dry weight".Objectives: To demonstrate the value of non invasive monitoring of hematocrit during HD in better understanding of hemodynamics in chronic HD patients , better estimation of the dry weight compared to conventional methods in pediatric age group and decreasing the frequency of intradialytic morbid events (IME).Methods : In this present study, the dry weight of 15 chronic HD pediatric patients was assessed using non invasive blood volume monitoring (NIVM) device and this was compared to the dry weight previously assigned to these patients based on conventional clinical methods. Changes in blood pressure readings together with the frequency of IME, before and after dry weight estimation using NIVM, were recorded and compared.