Mechanical ventilation is the most widely used supportive technique in intensive care units. Complications can occur at any stage of mechanical ventilation and is sometimes life threatening. Ventilator-Associated Pneumonia is a life-threatening complication with mortality rates of 33-50 %. The early application of nasal continuous positive airway pressure (nCPAP) reduces the need for subsequent endotracheal intubation, mechanical ventilation, and surfactant therapy and lower overall mortality, especially in infants with birth weight above 1500 grams.