36026

Living related liver transplantation in Egyptian patients the effect of graft size and hepatitis C infection on the outcome

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Tropical Medicine

Advisors

Abdel-Rahim, Ayman Y., Dous, Wahid H., El-Gabali, Hatem M.

Authors

Abdel-Bari, Amr Ahmad

Accessioned

2017-03-30 06:22:59

Available

2017-03-30 06:22:59

type

M.D. Thesis

Abstract

This study was conducted on the first 53 cases of adult to adult LDLT in Dar El Fouad hospital. The aim of the study was to investigate the incidence and morbidity of HCV infection recurrence post-LDLT in Egyptian patients and to determine the impact of graft volume on outcome. Recurrence of HCV was universal in terms of viremia. Clinical recurrence of HCV defined by evidence of viral replication by PCR, elevated transaminases, and confirmatory histology, was seen in 26.3% of recipients. Clinically recurrent HCV was mild. There was a significant correlation between mean actual graft weight and development of clinically recurrent HCV. There was a significant correlation between mean estimated graft volume and development of clinically recurrent HCV. There was a significant impact of the actual GRWR (<1 %, >1%) on the development of clinical HCV recurrence. Grafts with a GRWR of < 1% showed a higher incidence of clinical HCV recurrence than those with a GRWR of > 1%. There was a significant directly proportional correlation between estimated graft volume and the time of clinical recurrence of HCV. There was also a significant directly proportional correlation between actual graft weight and the time of clinical recurrence of HCV posttransplantation.

Issued

1 Jan 2005

Details

Type

Thesis

Created At

28 Jan 2023