The prevalence of allergic diseases seems to have increased particularly over the past 30-40 years. It has been known for decades that gut commensal microbes, colonizing the neonatal mammals, affect not only tolerance but also the development of systemic immune response there are lage geographical variations in the composition of human GIT microflora. It has been suggested that a reduced microbial stimulation during infancy and early childhood would result in slower post-natal development of immune response and development optimal balance between TH-l and TH2 like immunity. Aim to test the hypothesis that allergic diseases among children may be associated with difference in their microflora.