Toxocariasis is infection of human viscera by migrating larvae of Toxocara species, especially Toxocara canis through extra-intestinal tissues. A definitive diagnosis of visceral larva migrans (VLM) and ocular larva migrans (OLM) depends mainly on detecting specific antibodies in serum or ocular fluid. Therefore, the aim of this work was to determine the effect of somatic and metabolic (ES) larval antigens of T. canis on the cross-reactions encountered in IFAT and ELISA tests with sera of patients with other parasitic infections. It was also planned to find the sensitivity and specificity of those antigens implementing the above mentioned serodiagnostic techniques. This study included 160 cases; 80 cases suspicious of ocular and visceral toxocariasis, 40 cases of other parasitic diseases and 40 apparently healthy controls of same age and sex living in similar areas of the cases. The sensitivity of ELISA was 80% for VLM and 60% for OLM while that of IFAT was higher for VLM (93.3%) and lower for OLM (52.5%). The specificity of ELISA was found to be 100% whereas the specificity of IFAT test was 95.5% only.