Evaluation of the uterine cavity is mandatory when studying infertile patients. Likewise, assessment of the implantation site is an important step in the management of patients with diagnosed infertility, indeed uterine cavity pathologies such as fibroids, polyps and Müllerian anomalies can impair fertility and result in recurrent pregnancy loss and poor outcome of pregnancy. Thus, their detection and treatment are important in order to achieve therapeutic success. Hysteroscopy is the gold standard procedure for uterine cavity exploration. It can be performed in an office with minimal discomfort and at a much lower cost than in an operating room. Traditionally, uterine cavity was assessed by HSG. However, in the recent past, hysteroscopy is being increasingly used for direct visualization of uterine cavity and is considered superior to HSG by many workers. Our study was conducted on 30 females who attended the outpatient clinic in Cairo Universty hospital. Its objective was to assess the diagnostic accuracy of office hysteroscopy in determining the uterine cavity abnormalities. The study revealed presence of intrauterine polyps, submucous fibroids, intrauterine adhesions, Mullerian anomalies which was uterine septum. Some results were missed by standard infertility investigations i.e. hysterosalpingography. These lesions can be treated during hysteroscopy and their treatment may lead to successful conception as reported by some authors. Outpatient investigations may be favored by patients because they spend less time in the hospital; however it is important to tailor the outpatient investigation to suit the particular patient.