Phosphorus is one of the most abundant elements on earth. It exists in the body and food chiefly in the ionic state. Phosphate plays a vital role in several biological processes including energy and nucleic acid metabolism, Phosphate dietary intake has increased over the last 30 years and also may be underestimated because of the increasing contribution of food additives. Phosphate has been widely used as electrolyte replinsher, a buffer vehicle for injectable medicines and as food additive. Previous studies detected harmful effects resulting from the increase in phosphorus consumption. This study was conducted to demonstrate the histological, ultrastrctural and morphometric changes that may occur in the kidney of albino rats as a result of dibasic sodium phosphate administration. Twenty one adult male albino rats were divided into 2groups; Control group (n=6) and experimental group (n=15). Each rat in control group were given physiological saline at 4 ml\Kg once daily by intra peritoneal injection using a plastic syringe for 14 successive days. Each rat in experimental group were given dibasic sodium phosphate (Na2HPO4) solution at 4 ml\Kg once daily by intra peritoneal injection using a plastic syringe for 14 successive days. Kidney specimens were stained with Hx&E, PAS and Modified Von Kossa's stains. Ultrathin sections were prepared for E/M examination. The thickness of the Glomerular basement membrane and the parietal layer of Bowman's capsule were assessed by their optical density in PAS sections. The area percentage of the brush Border of Proximal tubules was determined in PAS sections and statistical analysis was performed. The dibasic sodium phosphate caused injury of the kidney in the form of glomerular atrophy, separation of glomerular tufts, widening of bowman's space and glomerular capillaries, focal thickening of both glomerular basement membrane and the parietal layer, loss of brush border of proximal tubules and effacement of foot processes of podocytes. So it is recommended to avoid food sources that contain high levels of phosphate additives to avoid deterioration of kidney function.