Pelvic organs prolapse etiology is multifactorial. The POP-Q is now the only widely accepted to quantify POP objectively. Imaging studies may be useful. Uterovaginal prolapse treatment is vaginal hysterectomy and repair. Post-hysterectomy vault prolapse treatment is sacrocolpopexy (abdominal or laparoscopic). Prosthetic materials have been used to reduce the high recurrence rates as mid-vaginal sling. Total vaginal mesh procedures as Prolift and Perigee & Apogee system are the most recent treatment reserved for 3rd and 4th stage POP.