Background: Ghrelin is an endogenous ligand of the growth hormone secretagogue receptor. Liver cirrhosis exhibits a characteristic malnutrition status This may cause deterioration of clinical functions with resultant poor prognosis Aim of the study: was to evaluate the changes in the serum ghrelin level in patients with liver cirrhosis in different Child classes and its correlation to the nutritional status. Conclusion: nutritional and metabolic abnormalities in cirrhotic patients may be dependent on the changes in the ghrelin level and ghrelin can be used as an indicator of anorexia and malnutrition in cirrhotic patients. Correction of the nutrient deficit can improve the clinical outcome. Therefore, nutritional advice by dieticians and supplementation of nutrients through oral feeding, enteral feeding, and/or administration of specially designed formulae should be taken.