MRI is establishing a role as a primary diagnostic technique with evidence showing MR to have advantages over computed tomography as regards diagnostic sensitivity and specificity for many pathologies of solid organs and so MRI is preferred when further characterization of these masses is needed. MRI has many sequences that help in detection of hepatic focal lesions and in reaching the diagnosis easily even without contrast injection or the need for biopsy. The clinical applications of diffusion-weighted imaging in the liver include detection and characterization of focal lesions as well as the emerging application in evaluation of post treatment tumor response.Diffusion-weighted magnetic resonance imaging established an important role in clinical use in the abdomen, particularly in the liver.