EUS combines two modalities: endoscopic visualization and high-frequency US. EUS has a significant impact on diagnosis and management of GIT tumors. Multiple studies suggest that EUS is superior to other imaging modalities for tumor (T) and lymph node (N) staging of luminal and pancreaticobiliary malignancies. The ultimate choice of staging modalities is largely dependent upon patient selection and local expertise. EUS continues to grow and develop, though relative lack of trained practitioners, high costs of EUS processors and long duration of maneuver.