Recently, three additional types have been delineated of patients who had a clinical diagnosis of the disorder but who presented clearly distinct features Diagnosis of osteogenesis imperfecta is chiefly suggested following the frequent occurrence of fractures and a family history of the fractures that constitute the most crippling complications of the disease. multidisciplinary team approach is essential for diagnosis, for communication with patient and parents, and to tailor treatment needs to the severity of the disease and the age of the patient.The causal defect of the disease cannot be corrected with medical treatment and, currently, only symptomatic therapy is available Three types of treatment are available: non surgical management surgery (intramedullary rod positioning, spinal and basilar impression surgery), and drugs to increase the strength of bone and decrease the number of fractures.