The rapid development of endovascular interventions and their adoption by vascular surgeons have revolutionized the treatment of patients with peripheral arterial disease. The superficial femoral artery (SFA) is one of the most commonly intervened-on arteries; however, the optimal approach for treating this artery is still debated.Percutaneous transluminal angioplasty (PTA) with adjunctive stenting is a well validated and increasingly used technology, and it is the technique most frequently employed for infrainguinal endovascular treatment. An alternative to transluminal angioplasty is subintimal angioplasty (SIA), also referred to as percutaneous intentional extraluminal revascularization. Novel technologies and refinements of previous technologies are enabling endovascular treatment for increasingly complex vascular pathology.The study was a prospective, non-randomized study performed at the Department Vascular Surgery in Kasr Al-Aini hospital between January 2012 and September 2012. The study group includes patients suffering from atherosclerotic occlusive disease affecting the femoropopliteal segment presented by chronic ischemic symptoms.The aim of this thesis is to study the efficacy and safety of the transluminal versus the subintimal techniques for the management of the femoropopliteal occlusive disease.