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Nephropathy in the course ofHenoch-Schönlein purpura

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Pediatrics

Advisors

Mahmoud, Samya S., Ahmad, Samar M., Ghubreyal, Emad E.

Authors

El-Shaikh, Lamyaa Mahmoud

Accessioned

2017-04-26 12:27:40

Available

2017-04-26 12:27:40

type

M.Sc. Thesis

Abstract

Henoch-Schönlein purpura (HSP) is a non thrombocytopenic, purpuric, and systemic vasculitis that occurs most commonly in children. It is an acute immunoglobulin A (IgA) mediated leukocytoclastic vasculitis that affects primarily children. It is frequent in the first decade of life; with a reported incidence of 13.5 per 100,000.The onset is often following an upper respiratory tract infection.The dominant clinical features of HSP are cutaneous purpura, arthritis, abdominal pain, gastrointestinal bleeding, orchitis, and nephritis.Although the prognosis for unselected children with Henoch-Schönlein purpura (HSP) is relatively good, severe nephritis remains the major cause of morbidity and mortality in patients with HSP. Renal involvement can occur in 20 to 34 percent of children with HSP. Severe abdominal symptoms, an age of more than 4 years, and persistent purpura increased the risk of renal involvement.

Issued

1 Jan 2009

DOI

http://dx.doi.org/10.21473/iknito-space/32394

Details

Type

Thesis

Created At

28 Jan 2023