Traumatic brain injury is a leading cause of death and disabilityamong young people all over the world, especially those with concomitantelevated intracranial pressure and decreased cerebral blood flow. Thetraditional means of clinically identifying neurological events is byconducting a periodic examination to detect neurologic deterioration.However, because of the high sensitivity of the brain to ischemia and anoxia,the reliance on intermittent examination may not immediately detectdeterioration and therefore risks neurological damage to the patient. Variousneurological monitors are effective in detecting impending changes in brainelectrical activity, cerebral ischemia, and anoxia, which make it possible thatthe onset of such neurological insult maybe detected earlier. It was proventhat using these monitors in the ICU has dramatically improved the qualityof patient care and outcomes. This essay will summarize the technicalaspects of I.C.P., C.B.F. and brain tissue Po2 monitoring and their role in theclinical management of brain injured patients.