Acute leukemias are clonal expansions of uncommitted or partially committed haematopoietic precursor cells. Abnormalities in the control of programmed cell death (apoptosis) play an important role in leukemogenesis. Survivin is a member of Inhibitor of Apoptosis Proteins (IAP) family. Survivin prevents apoptosis by blocking caspase activity. Dramatic overexpression of Survivin was demonstrated in solid tumours of pancreas, oesophagus, lung as well as in leukemias and lymphomas. The present study assessed Survivin gene expression using Real-Time PCR.