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New trends in bridging the gap in peripheral nerve repair

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

General Surgery

Advisors

Gouhar, Raafat R., Muhammad, Ashraf E., Ayyad, Muhammad H.

Authors

Ebrahim, Muhammad Ebrahim

Accessioned

2017-04-26 12:27:39

Available

2017-04-26 12:27:39

type

M.Sc. Thesis

Abstract

Complete nerve injury can be defined as a defect that results in a disruption of a nerve such that it can no longer transmit an action potential. Peripheral nerves are fragile and can be damaged by pressure, stretching, or cutting. Injury to a nerve stop signals to and from the brain, resulting in loss of function in the distribution of the injured nerve. The goal in repairing the nerve is to reconstruct the continuity of it so that new fibers can grow in correct direction and the nerve can work again. (Angela 2005)Direct tension free repair by suturing of the proximal and distal nerve stumps is the first choice in nerve repair if the situation allows. The gap is simply the distance between ends that need to be closed. If the nerve is left in the severed condition, it retracts over time, increasing the gap size due to the elastic properties of the epineurium and joint movement. When the gap size is larger, more of a bridge must be filled and the prognosis is worse. The goal of surgical nerve repair is axonal growth through the direct repair or replaced conduit. If no conduit is present, nerve regeneration fails in favor of neuroma formation. (Ang 2001)Many different techniques have been developed in bridging the gap including approximation, nerve grafting, nerve transposition, synthetic conduits (absorbable and non absorbable), autogenous vein graft and muscle graft depending on several parameters, in particular the type and location of the nerve and various patient factors. (Dagregorio 2004)

Issued

1 Jan 2009

DOI

http://dx.doi.org/10.21473/iknito-space/32347

Details

Type

Thesis

Created At

28 Jan 2023