The aim of this work was to detect if there is possible role of FGM (female genital mutilation) on FSF (female sexual function).We used questionnaire of 50 items to assess FSF in different phases and some questions were related to FGM. 150 circumcised females and 50 uncircumcised females from Kasr ElAini Hospital gynecology department have answered the questionnaire by interview. The results of study can be summarized as follows: there were no statistically significant difference in sexual functions between circumcised group and uncircumcised in all aspects of sexual functions that include desire, excitation, vaginal lubrication, orgasm, and occurrence of pain related to coitus. Also, there were no statistically significant differences in sexual function between type 1 circumcised females and uncircumcised females group in all aspects of sexual functions, but there were statistically significant difference between type 2 circumcised females and uncircumcised females in difficulty in lubrication (P<0.04), and difficulty in reaching orgasm (P<0.003). Also with comparing type 1 circumcised females with type 2 circumcised females there were statistically significant difference between both groups in complications following circumcision operation (p<0.000), difficulty in lubrication (p<0.001), and difficulty to reach orgasm (p<0.01).