Single-photon emission computed tomography (SPECT) is accurate methods for detecting cancer and related metabolic abnormalities, but they often do not provide the anatomical landmarks needed to precisely localize lesions. Computed tomography (CT) scan, on the other hand, offer excellent anatomicdetail but are less sensitive because they do not provide functional detail. Hybrid imaging in oncological applications improve the anatomical landmarks as well as the attenuation and accurate assessment of radiation dosimetry. The system will lead medical imaging to new horizons.