Diabetes is a risk factor in 10-30 % of patients who develop heart failure.In type II diabetes, isolated abnormalities of diastolic relaxation in theabsence of symptoms or signs of heart disease suggest a diagnosis of'diabetic cardiomyopathy'. This is thought to result frommicroangiopathy, deposition of collagen, decreased expression/activationof the potassium channel and sodium pump and decreased myofilamentcalcium (Ca+²) sensitivity.Diastolic dysfunction in diabetic patients is believed to represent anearlier stage in the natural history of diabetic cardiomyopathy (Cosson etal., 2003), and its timely recognition may help to avoid or significantlydelay the onset of CHF.Previously published reports about the prevalence of LV diastolicdysfunction in diabetes are conflicting, mainly because of theconfounding effect of systemic hypertension and CAD that frequentlycoexist with diabetes and have significant effects on cardiac diastolicphysiology.