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New implications of Alpha 2 agonist drugs

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Anesthesiology

Advisors

Mahmoud, Maher F., Husain, Abdel-Fattah A., Esmaeil, Maha M.

Authors

Aly, Muhammad Metwalli

Accessioned

2017-04-26 12:03:55

Available

2017-04-26 12:03:55

type

M.Sc. Thesis

Abstract

The anesthetic use of α2 adrenergic agonists has been of considerable and sustained interest for the last fifteen years. They are nowadays familiar to many anesthetists due To their different sedative, hemodynamic and analgesic properties. The exact role of α2 agonists especially clonidine and dexmedetomidine remains a matter of debate and poorly defined despite considerable clinical evidences. The net effect of activation of α2 adrenergic receptors is modulation of sympathetic nervous system activity. Manifestations of thisresponse include decrease cardiac out put, heart rate and systemicvascular resistance, also reduction of blood pressure and systemicvasodilatation.

Issued

1 Jan 2008

DOI

http://dx.doi.org/10.21473/iknito-space/31967

Details

Type

Thesis

Created At

28 Jan 2023