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Value of fetal umbilical, middle cerebral artery and ductus venosus blood flow in predicting neonatal hypoxia in growth retarted fetuses : Correlation with neonatal outcome

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Obstetrics & Gynecology

Advisors

Muhammad, Aumar A., Qandil, Hesham A., El-Ebrashi, Alaa N.

Authors

Eid, Tamer Muhammad

Accessioned

2017-07-12 06:40:16

Available

2017-07-12 06:40:16

type

M.D. Thesis

Abstract

Objective : This study examines the relationship between arterial and venous Doppler results in IUGR fetuses and correlates their abnormalities with umbilical artery PH at birth to guide timing of delivery of these fetuses.Design : Prospective observational study. Setting : Mahmoud hospital. Patients And Methods : 50 patients diagnosed with intrauterine growth restriction (IUGR); and other 20 control cases matched for age parity and gestational age, all patients underwent uniform antenatal assessment protocol that includes a four component biophysical profile score, cardiotocography and umbilical artery (UA), middle cerebral artery (MCA) and ductus venosus (DV) Doppler ultrasound studies.All patient were delivered by caesarean section. Samples were obtained from the umbilical cord for cord artery PH. Apgar scores at 1 and 5 minutes were recorded.Outcome : Correlation of Doppler on the three different vessels UA, MCA and DV results and cord blood PH were analyzed.Results : UA Doppler abnormality was the most commonly encountered Doppler abnormalityWith UA Doppler statistical significance is found with the APGAR score at 1 min. and 5 min (P value <0.05) as an outcome parameters compare in cases with abnormal UA doppler, while there was no statistical significane with neonatal PH and neonatal deaths as an outcome parameters when we compare cases with normal and abnormal UA dopplerIn cases with abnormal MCA or DV Doppler, statistical significance was reflected on all the outcome parameters.Conclusion of our study is that there is an important association between MCA and DV abnormalities and adverse neonatal outcomes suggesting that the assessment of these vessels is important to determine the timing of delivery especially premature.

Issued

1 Jan 2010

DOI

http://dx.doi.org/10.21473/iknito-space/35245

Details

Type

Thesis

Created At

28 Jan 2023