Vascular calcification is frequent in patients with chronic kidney disease (CKD). The presence and extent of vascular calcifications are predictors of cardiovascular and all-cause mortality in stable end-stage renal disease patients on hemodialysis. Accordingly, the present study was designed to examine the possible relation between vascular calcifications, 25-hydroxyvitamin D3 [25(OH)D3] serum level and the cardiovascular risk factors associated. In this study, the significant increase in LVMI in the Dialysis group is inversely correlated to the vitamin D level ; pateints with low levels of vitamin D have a high Left ventricular mass index. A significant negative correlation was observed also between plasma levels of vitamin D and intimal media thickness.