This study included 50 diabetic pediatric patients (age ranged from 4 to 16 years ) complained of gastrointestinal symptoms, who presented to the endocrinology unit at Cairo University Specialized Pediatric Hospital with gastrointestinal complaints and had been tested for the presence of H. pylori infection by the C 13 urea breath test. Only Twelve positive cases approved for undergoing endoscopy for confirming H. pylori infection by biopsy specimens obtained by upper gastrointestinal endoscopy and for assessment of gastritis. The overall incidences of H.pylori infection in all children (cases and controls) we have studied were 55 % In our study no statistically significant difference was found regarding H .pylori positivity between diabetic cases and controls, as 6o% of cases were positive compared to 45% of controls