MSCT signs of appendicitis include an appendix measuring greaterthan 6 mm in diameter, failure of the appendix to fill with oral contrastmedium or air up to its tip, and enhancement of its wall with intravenouscontrast medium.Surrounding inflammatory changes, presence of an appendicolith andcecal apical changes are helpful signs in diagnosing acute appendicitis.MSCT is useful in diagnosing acute appendicitis, but also inevaluating a number of conditions that mimic appendicitis clinically, eg.cecal diverticulitis, sigmoid diverticulitis, torsion of Meckel’sdiverticulum, primary epiploic appendagitis, infectious colitis,gynecologic disorders, right lower lobe pneumonia, crohn’s disease, andacute cholecystitis.MSCT also is useful in diagnosing complications of acuteappendicitis e.g. appendiceal perforation, phlegmon or an abscessformation, hepatic abscess, and Pyelophlebitis.MSCT can be used in appendiceal complications to guide abscessdrainage. Preference to use CT because of the more precise definition ofthe access route to the collection.To conclude MSCT is helpful for accurate and prompt diagnosis insuspected cases of acute appendicitis, its complications and conditionsthat mimic appendicitis.