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Microalbuminuria as a risk factor for coronary heart disease in diabetics

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Internal Medicine

Advisors

Wassfi, Ayda A. , Nassef, Sahar Abdel-Rahman , Khalil, Muna S.

Authors

Amin, Hatem Gamal-El-Din Mahmoud

Accessioned

2017-03-30 06:20:12

Available

2017-03-30 06:20:12

type

M.Sc. Thesis

Abstract

In this study, 20 type-2 diabetic patients with coronary heart disease (CHD) and 25 type-2 diabetic patients without CHD were compared as regards microalbuminuria, and the relationship between this risk factor and other cardiovascular risk factors. The results showed that; Urinary albumin excretation in type-2 diabetics with CHD was significantly higher than those without CHD (P<0.003). Again type-2 diabetics with CHD showed statistically significant higher Urinary Albumin/ Creatinine ratio (P<0.006), serum fasting B.G. (P<0.043), Cholesterol (P<0.002), triglycerides (P<0.023), LDL (P<0.007), older age (P<0.0001), higher BMI (P<0.028), greater left ventricular diameter during diastole (P<0.015) and systole (P<0.004), and left vent. mass (P<0.005), lower ejection fraction (P<0.005), and fractional shortening (P<0.004), thicker common carotid intimal media (P<0.018) and internal diameter (P<0.0001), when compared to type-2 diabetics without CHD.Again, those with CHD showed statistically significant higher BMI (P<0.0001), serum Cholesterol (P<0.0001), triglycerides (P<0.002), LDL (P<0.0001), fasting (P<0.0001), post prandial (P<0.0001) blood glucose, glycohemoglobin (HBA1c) (P<0.0001), urinary albumin excretion (P<0.018), A/C ratio (P<0.031), greater interventricular septum during diastole (P<0.020), and systole (P<0.006), left ventricular mass (P<0.002), lower ejection fraction (P<0.0001), and fractional shortening (P<0.0001), thicker common carotid intimal media (P<0.0001) and internal diameter (P<0.012) when compared to the control group.

Issued

1 Jan 2002

Details

Type

Thesis

Created At

28 Jan 2023