Toxicogenomics is described as a discipline combining expertise intoxicology, genetics, molecular biology, and environmental health toelucidate the response of living organisms to stressful environments. Asthis emerging field rapidly develops, it is important to assess howtoxicogenomic data can be applied to improve risk assessment andprovide a means for personalization of medicine. Toxicogenomicsencompasses technologies that enable scientists to measure geneticsequencevariation (genomics), gene transcription (transcriptomics)protein expression (proteomics), and metabolite profiles (metabolomics)in response to chemicals and other stressors. These "omics" technologiesprovide an enormous amount of information that need to be interpretedusing bioinformatics tools to better prioritize data and understand achemical’s progression from the environment to the target tissue withinan organism and ultimately to the key steps that trigger an adverse healtheffect. Toxicogenetics deals with the person himself, it promises toprovide the specific polymorphisms responsible for the abnormal reactionof some individuals to certain chemicals. In the near future, through thecombined efforts of both toxicogenomics and toxicogenetics, there willbe a great breakthrough in the field of medicine, providing a personalizedmedicine with the best effect and the least side-effect.