Lupus nephritis is a frequent and serios complication in virtualmost children with SLE , ranging from minimal involvment toprogressive renal failure . Because of undetected incidence oflupus nephritis and its epidemiology among Egyption children, this study included 100 patients with lupus nephritisfollowing in the rheumatology clinic at cairo universitychildren hospital and aimed to describe their different clinical,laboratory and pathological presentation , to investigate theclinicopathological correlation and medication received andfollow up achieved as well.