The aim of this study was to compare clinically and radiographically the stability of resorbable versus Titanium osteosyntheses for the fixation of Le Fort I osteotomies. The study was conducted on 12 adult patients. Patients were selected from the Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Oral and Dental Medicine, Cairo University, All patients had bimaxillary growth disturbances planned for correction by a maxillary Le Fort I advancement and mandibular BSSRO surgeries. The patients were divided into two groups according to the means of internal fixation. The maxilla was fixed with 2.0 mm biodegradable and titanium bone plates and screws in groups A and B respectively. Clinical and radiographic follow-ups in the form of lateral cephalometric and panoramic radiographs were taken immediately post-operatively, three, six, and nine months post-operatively. The results showed there was no significant difference in postoperative skeletal horizontal changes (relapse) as indicated by the SNA angle difference through the whole follow-up periods between the two groups.