Objective: The present study was conducted to evaluate the use of deproteinized bovine bone xenograft mixed with autogenous mandibular symphyseal bone graft in secondary maxillary alveolar cleft reconstruction compared to the standard anterior iliac crest autogenous graft. Patients & Methods: 10 patients of (mean age 9.3 years ± 1.33) with unilateral maxillary alveolar cleft defect were included in this study. They all required secondary alveolar cleft grafting. Patients were divided into 2 equal groups. Group A received anterior iliac crest graft. Group B received mandibular symphyseal bone mixed deproteinized bovine bone in a 1:1 ratio. For each patient, 3 CBCT scans were ordered: preoperatively, immediately postoperatively and 6 months postoperatively. Volumetric and densitometric measurements were made. Data were collected and statistical analysis was performed to compare the data obtained from each group alone as well as the data obtained from both groups together. Results: No statistical significant difference was found when data were compared within the same group. Upon comparing the 2 groups, there was also no significant difference found. Conclusion: Composite symphyseal bone mixed with deproteinized bovine bone in a 1:1 ratio gives comparable results to anterior iliac crest graft in secondary alveolar cleft reconstruction