This study aimed to evaluate and compare the stability of the Matrix Orthognathic (BSSO) plating system versus bicortical screw fixation after bilateral sagittal split ramus osteotomy (BSSRO). Twelve female patients with skeletal dentofacial deformities referred to the outpatient clinic of Oral & Maxillofacial Surgery department, Faculty of Oral and Dental Medicine, Cairo University, suffering from skeletal class II deformities requiring Bimaxillary orthognathic surgery with mandibular advancement utilizing (BSSO). According to the type of fixation, our patients were divided into two equal groups (six patients each). In Group I bone fixation was achieved using the Matrix orthognathic plate and six 2.0 mm monocortical screws. Bone fixation was achieved in Group II by using three positional bicortical screws (2.0 mm in diameter). The subjects of both groups were evaluated and followed up both clinically and radiographically immediately 24 hours and six months postoperatively. The obtained results were collected, tabulated for further statistical analysis. Subjects of both groups showed clinical improvements in the form of facial esthetic improvement, balanced facial proportions, functional and occlusal stability during the follow-up period. There was no statistical difference between both groups. It was concluded that matrix orthognathic plate with 2.0 mm monocortical screws provide sufficient stability for early mobilization, high elasticity to prevent medial or lateral condylar dislocation and the possibility of minor post-operative corrections.