Transferrin receptor (TfR) is a disulphide linked glycoprotein which can be found in two forms; the cell surface bound form and the circulating form in serum.TfR are present on proliferating cells; normal and malignent.Decreased TfRs level on peripheral blood lymphocytes have been reported in iron deficiency anemia(IDA). We looked at the mean expression of TfRs on peripheral blood lymphocytes in 40 children with IDA ,further division of cases into 2 subgroups depending on HB level,26 patients with HB ≥ g/dl ( group A),and 14 patients with < 8.6 g/dl (GROUP B ) and 15 control subjects.Mean expression of TfRsin group A was significantly higher than group B but both values were significantly lower than control group (p<0.01).