The role of surgery for esophageal varices with bleeding has decreased in the face of effective injection sclerotherapy. Cases not responding to sclerotherapy need surgery. Decompressive portasystemic shunt which reduce the high portal pressure, is the most effective surgical treatment. In this study mesenterico-renal shunt technique is described. This consists of end to side anastomosis between the termination of the divided inferior mesenteric vein, in continuity with the splenic vein, and the side of left renal vein, 5 patients with recurrent variceal bleeding underwent mesenterico-renal shunt 3 males and 2 females with ages between 21-45 years. This study was shown improvement of liver functions, there was no rebleeding episode except in one case and postoperative endoscopy showed improvement of the grade of varices and markedly improvement of the degree of gastropathy. Postoperative duplex study showed patency of the all shunts. However, a large serious of patients is recommended for evaluation of this shunt procedure and clinical comparison with other procedures as TIPS or selective shunt procedure is recommended. Moreover, the study of hemodynamic of bleeding flaw in the portal circulation is recommended after this shunt to find explanation of the positive results shown in our study.