Objective: To detect the three- dimensional effects of FFRD and the efficiency of indirect mini implants anchorage in minimizing the dento-alveolar side effects of the appliance therapy.Material and Methods: The sample consisted of 43 skeletal Class II females due to deficient mandible. They were randomly allocated into three groups; 16 patients (13.25± 1.12 years of age) were treated with FFRD alone (Forsus group), whereas 15 subjects (13.07 ± 1.41 years of age) were treated with FFRD and mini implants (FMI group) and a control sample of 12 untreated Class II subjects (12.71 ± 1.44 years of age). CBCT radiographs were up taken immediately before insertion and after the appliance removal. Three dimensional analysis was used including skeletal, dento-alveolar and soft tissue linear and angular measurements. Statistical tests were used to evaluate changes before and after the treatment in each group and to compare between the groups.Results: Class I molar relationship and overjet correction were achieved in 88 % of the cases. No significant differences in the skeletal mandibular effects between the three study groups. Significant increase in the lower facial height and gonial angle, decrease in maxillary width and restraint in the A-P maxillary position were noted in the FMI group. Retroclination and extrusion of maxillary incisors, distalization of maxillary molars and extrusion of mandibular molars were significantly more evident in the FMI than the Forsus groups. Proclination and intrusion of mandibular incisors were significantly greater in the Forsus group than in the FMI group. Conclusion: Class II correction was mainly dento-alveolar with minimal sagittal skeletal effects in both treatment groups. Unfavorable proclination and intrusion of mandibular incisors was effectively minimized with the utilization of indirect mini implants anchorage.