Background/objective: Traumatic dental injuries (TDIs) of permanent teeth in children is a significant dental public health problem worldwide. No published study or data was found regarding this problem in Egypt. Therefore, this study was done to determine the prevalence, types, causes and other factors associated with TDIs in a group of Egyptian children attending dental hospital of Cairo University. Materials and Methods: A Cross-sectional observational study was done in Pediatric dentistry and Dental Public Health Department, Cairo University on children between ages 7-14 years presented with traumatic dental injuries in their permanent teeth throughout a year from January 2015 to December 2015. An interview administered questionnaire and clinical examination were done for each patient. Results: The prevalence of TDIs was found to be 7.7% that represents 346 children with male to female ratio 1.6:1. Only 13.1% of children presented early within 24 hours. The total number of affected teeth was found to be 526, the majority 86% of traumatized teeth were upper centrals. The most common dental injury was enamel-dentin fractures 40.9% followed by complicated crown fractures 35%. Falls accounted for 56.9% of causes of TDIs, and the majority of them 48.2% occurred at homes. Conclusion: Although in this study the prevalence of TDIs was relatively low compared to other studies, it was found that the majority of children presented late. Therefore, awareness programs needs to be carried out regarding the importance of emergency care and the advantages of early treatment of TDIs to parents and school teachers.