Statement of the problem: Successful long-term bonding to zirconia ceramic remains a challenge, requiring special surface treatment methods. The methods used to increase micromechanical retention to silica based ceramics do not always produce the required roughness and bond strength to zirconia ceramics. Objective: The present study was an attempt to improve the bond strength of zirconia-based ceramic restorations (Ice-zirconia- zirkonzahn ) to resin cement. Materials and Methods: twenty one zirconia discs received 3 different surface treatments: group 1- sandblasting with110 um aluminum oxide particles; group 2- silica coating (cojet system) and group 3- laser irradiation (CO2 laser). The ceramic discs were cemented to natural teeth by resin cement ( RelyX Unicem).Scanning electron microscope was also performed to evaluate the surface morphology changes. Shear bond strength was recorded using a universal testing machine at a cross-head speed of 0.5 mm/min and expressed in megapascals (MPa). Results: All groups yielded statistically significantly different roughness mean values: group 1(219.00 ± 14.8 μm); group 2(187.26 10.72041μm); group 3 (262.11 ± 31.675μm) (ANOVA and Newman-Keuls test; p < 0.05). Also, all groups yielded statistically significantly different shear bond strength mean values: group 1(18.69 ± 2.47 MPa); group 2(14.51 ± 1.7 MPa); group 3 (12.69 ± 2.439 MPa) (ANOVA and Newman-Keuls test; p < 0.05) Conclusion: Increasing surface roughness of zirconia ceramics using laser irradiation had no significant effect on the shear Bond strength. Sandblasting remains the most suitable and the easier method for enhancing the bond strength between zirconia ceramics and resin cement.