Objective: to compare and evaluate the stress distribution to the supporting structures around three implants supporting an obturator under vertical loading using strain gauge technology in three various implant distributions. Methods: The experiment was carried out on an Aramany class I maxillofacial defect of an edentulous acrylic model, with five installed implants equally distributed in the edentulous non defect side. The defect area was covered with a silicon based soft liner to simulate the covering mucosa. The obturator was designed to have a horse shoe shaped occlusal plate extending to the first molar region. Dimples or depressions were created in the canine and first molar regions of the occlusal plate to accommodate the loading points. The model was then prepared for strain gauge installation. Ten gauges were bonded to the different implant surfaces. The universal testing machine was used to apply both compressive loads onto the prepared notches during the strain measurement tests. The loading device was adjusted to apply a static load of 100 N to the loading points. The previous test was repeatedly done for three groups each of which has three implants with a different implant distribution. Finally, the collected data was tabulated and statistically analyzed. Results: Statistical analysis of the collected data showed that microstrain values of the third group was significantly higher than the two other groups when the load is applied in the canine region. However the microstrain values are higher in the first group compared to the other groups when the load is applied in the molar region. Conclusion: The stresses around the implants in the widely distributed locations were higher than implants in anterior or posterior distributions when the load is applied in the canine region. The stresses around the implants in the anterior implants were higher than the widely distributed implants and posterior distributions when the load is applied in the molar region.