The aim of this comparative study was to evaluate radiographically the effect of two different occlusal schemes (lingualized and monoplane) on the supporting bone around early loaded mini-implants supporting mandibular overdentures. Fourteen completely edentulous male patients were selected from the outpatient clinic of the Prosthodontic Department, Faculty of Oral and Dental Medicine, Cairo University according to certain criteria. Patients were divided randomly into two equal groups (seven patients each). Four mini-implants were placed in each patient at the inter-foraminal area. Group I: Patients received mandibular mini implant-supported overdentures with their occlusal scheme set according to the lingualized occlusal concept. Group II: Patients received mandibular mini implant-supported overdentures with their occlusal scheme set according to the monoplane occlusal concept. The early loading protocol was implemented and patients were asked to recall 1 week after implant placement for denture delivery and pick-up procedures. Each case was evaluated radiographically immediately after denture insertion (0 month), then 3 months, 6 months and 9 months after denture insertion. Radiographic evaluation included assessment of bone density and bone height changes around the mini-implants in the two groups. The Digora computerized system, the Rinn XCP periapical film holder and individually constructed radiographic acrylic templates were used for making standardized reproducible serial digital images by applying the long cone paralleling technique. Data were collected tabulated and statistically analyzed. In general, both occlusal schemes demonstrated fairly promising results in early loaded mini-implant supported mandibular overdentures. Bone height decreased slightly in both groups but the total amount of bone loss was lower in group I than in group II. Statistically however, there were no significant differences between the two groups as regards bone height measurements. Bone density decreased during the first three months in both groups. This was followed by a gradual increase with the greater increase being recorded for group I (lingualized group) followed by group II. Statistical analysis revealed a significant difference between the two groups at the end of the study period only. Within the limitations of this study, it can be concluded that:Early loading of mini- implant supported mandibular overdentures could be considered a practical and a promising treatment modality. Both occlusal schemes demonstrated a fairly good bone reaction as regards bone height and density. However, a slightly more favorable bone reaction was observed in the lingualized occlusion group than in the monoplane occlusion group.