Objectives: The aim of the study was to evaluate the influence of different surface treatments on micro-shear bond strength between three ceramic systems and resin cement Materials and Methods: Three ceramic materials , a leucite reinforced glass ceramic(Cerinate porcelain), lithium disilicate glass ceramic (IPS e.max press) and Prettau Zirconia were used. A total of Eighteen all-ceramic disc specimens that measure approximately 1 mm height X 1 cm diameter were constructed. The disc specimens were divided according to the all-ceramic system into three equal groups:Group I; Cerinate porcelain, Group II: lithium disilicate glass ceramic and Group III: zirconia. The flat round discs of each group were randomly further subdivided into three equal subgroups according to the surface treatment protocol: Subgroup A: air borne particle abrasion followed by hydrofluoric acid etching, Subgroup B: hydrofluoric acid etching and Subgroup C: silica coating using Cojet system. After different surface treatments, scanning electron microscopic analysis was performed for qualitative examination. Computer software was used to calculate average of the surface roughness (Ra), expressed in μm, which can be considered as a reliable index of surface roughness. Dual cured resin cement (RelyX Unicem), was mixed and applied to the treated ceramic discs following the manufacturer instructions. Micro-shear bond strengths was measured at crosshead speed of 0.5 mm/min. The mode of failure was determined by scanning electron microscopy. Results were analyzed using two-way Analysis of Variance (ANOVA) and post-hoc Tukey´s test. Results: air borne particle abrasion followed by hydrofluoric acid etching was associated with statistically significantly higher mean microshear bond strength values 26.4 MPa than silica coating 23.8 and hydrofluoric acid etching groups 20.1. ANOVA indicated the influence of surface treatment was significant (p < 0.05). Conclusion: Different surface treatments showed significant effect on the micro-shear bond strength between the tested all-ceramic systems and resin cement. Among the investigated surface treatments, air borne particle abrasion followed by hydrofluoric acid etching was the most effective surface treatment in terms of bond strength increase.