Aim of the Study: The aim of this study was to compare the effect of glass ionomer varnish versus self adhesive nanofilled coating on fluoride release from conventional and resin modified glass ionomer cements.Material and Methods: 48 samples were prepared; 24 samples from resin modified glass ionomer cement (Fuji II LC) (group 1) and 24 samples from conventional glass ionomer cement (Fuji IX GP Fast) (group 2). Each group was further subdivided into 3 subgroups. From each group; 8 samples were coated with glass ionomer varnish (Copal Varnish LC), 8 samples were coated with self adhesive nanofilled coating (G-Coat Plus) and 8 samples were left uncoated. Each sample was stored into 3 ml of deionized water. Fluoride release was measured using fluoride ion selective electrode daily for the first week then weekly for the first month. Data were analyzed using Two-way ANOVA and Duncan's post-hoc test. The significance level was set at P ≤ 0.05.Results: For the same time intervals, resin modified glass ionomer cements showed higher fluoride release more than conventional glass ionomer cements for the same time intervals. Self adhesive nanofilled coated samples showed less fluoride release than varnish coated samples. Moreover, both coating showed a decrease in the fluoride release amount compared to uncoated samples.Conclusion: fluoride release from glass ionomer cements depends on the type of glass ionomer cement, time and type of coating applied over them.