The alveolar bone loss at maxillary anterior area result in a situation in which the implant to be placed in a favorable functional and aesthetical position, containing parts of its surface clear of bone coverage, originating bone imperfections such as dehiscences and fenestrations. This study aims to overcome this problem by simultaneous implant placement and horizontal ridge augmentation using. enzyme-deantigenated equine spongy bone granules Bio-Gen (equine xenografts). Used in association with a lyophilized equine collagen membrane for correction of dehiscence/ fenestration defects associated with implant placement in anterior maxilla. , this clinical study suggests that enzyme-deantigenated equine spongy bone granules (Spongy BIO-GEN®, BGS-0.5 granules of 0.5-1 mm) used in association with a lyophilized equine collagen membrane (BIOCOLLAGEN® membrane) for correction of dehiscence/fenestration defects associated with implant placement is not clinically acceptable because of the minimal bone gain.