Aim of the study: The purpose of this study was to evaluate clinically and radiographically the periapical healing of traumatized young permanent anterior teeth in children by the use of Sodium hypochlorite or sodium hypochlorite in conjunction with MTAD as irrigating materials and Bioactive Glass or Mineral trioxide aggregate as an obturating materials. Materials & Methods: Forty four subjects having forty eight immature maxillary anterior permanent teeth aged between eight and thirteen years with mean age of (10.2 ± 1) have been selected in this study. The selected subjects were divided randomly into four groups according to the irrigating and obturating materials. Group A were irrigated with (NaOCl) and apically filled with (MTA), Group B were irrigated with (NaOCl) and apically filled with (BAGs), Group C were irrigated with (NaOCl+ MTAD) and apically filled with (MTA) while Group D were irrigated with (NaOCl+ MTAD) and apically filled with (BAGs). Subjects were followed for one year both clinically and radiographically immediately postoperatively, 3 months, 6 months and 12 months postoperatively using DIGORA system. Radiodensitometric measurements were made for each subject. Data were collected and statistical analysis was performed to compare the data obtained from each group alone as well as the data obtained from the four groups together. Results: The clinical and radiographic success was observed in (MTA) groups were higher than that observed in the (BAGs) groups with no statistical significance difference between the two groups. (MTAD) groups showed higher clinical success than NaOCl groups with also no statistical significance difference between the two groups. Conclusion: MTA and Bio Active Glass are promising materials and play important role in healing and sealing of root canal and thus saving patient from psychological trauma of surgical procedures.