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Assessment of resting myocardial function in patients with liver cirrhosis : A combined echocardiography and tissue Doppler imaging

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Cardiology

Advisors

Abdel-Ghany, Muhammad M. , El-Sirafi, Magdi A. , Saleh, Heba F.

Authors

El-Maymouni, Taha Ahmad Aly

Accessioned

2017-07-12 06:40:36

Available

2017-07-12 06:40:36

type

M.Sc. Thesis

Abstract

Aim of the study: To study the cardiac function in patients with liver cirrhosis. Methods: Thirty five patients with liver cirrhosis, referred to as group I (G 1), were selected. They were subdivided according to Child-Pugh classification into 3 groups: A, B, and C. sixteen healthy subjects, referred to as group II (G II), were selected as a control group. All persons were examined by resting ECG, abdominal ultrasound, laboratory tests, and echo-Doppler evaluation of systolic and diastolic functions of both ventricles using 2-D, M-mode, conventional Doppler, and tissue Doppler parameters. Results Compares the echocardiographic parameters of the cases and the controls and there was a statistically significant difference in the following parameters LA volume, LV SWT, LV PWT, EF eyeball %, MA wave, M E/A, FAC, DT, TAPSE, LT S wave, LT A wave, HR, COP and SV (p<0.05) but the difference was not statistically significant regarding EDD, ESD and EF M-m%, ME wave, E/E, RVD prox. and LT E wave (p>0.05). The electrocardiographic findings of the studied cases. PR interval ranged from 112 to 200 with a mean value 155.3 (±4.8), the mean QT interval was 361.5 (±6.7) and mean QTC was 444.6 (±6.1) and ranged from 379 to 510. Among the studied cases, a highly significant correlation was found between severity of LCF and E/E’ (r=0.335, p<0.05), cardiac output (COP) (r=0.384, p=0.02),, Stroke volume (SV) (r=0.503, p=0.002), QTC (r=0.443, p=0.008), and orthostatic hypotension (r=0.736, p<0.0001) and No significant correlation was found between severity of LCF and, PR interval, LA volume, EF, E/A, LT S, FAC, TAPSE, LT E’ or LT A’. Conclusion: Many cardiovascular abnormalities occur in patients with liver cirrhosis that mandate echocardiographic evaluation especially in cases who undergo any procedure which may affect the hemodynamics.

Issued

1 Jan 2012

DOI

http://dx.doi.org/10.21473/iknito-space/35644

Details

Type

Thesis

Created At

28 Jan 2023