Introduction: Percutaneous transluminal angioplasty is an effective therapy in restoring the function of failing arteriovenous fistulae. Compared to surgery, PTA has several advantages including the fact that it is relatively simple, less invasive, short procedure causes less stress to the patient, enables immediate dialysis without the need for central venous catheters; reduce the risk for infections and save the patient veins. However, the open surgical and endovascular treatment should be viewed as complementary approaches rather than a competitive one. Patients and Methods: 40 patients with 40 dysfunctional fistulas were suitable for the study. All of them were treated using endovascular techniques. Results: AVFs can be successfully salvaged in our study using PTA in a success rate reach 92.5%, with a primary patency rate 18 months. Conclusion: with meticulous pre-operative monitoring and periodic surveillance the chance for access dysfunction will be minimized, and even with detection of access dysfunction percutaneous angioplasty PTA is an effective therapy in restoring the function of failing AVFs.