The objectives of this work were to study the suicidal spectrum phenomenon among a sample of patients frequenting the psychiatry outpatient clinic in Kasr El-Aini Hospital, and to assess the impact of self-esteem, the ability to cope with psychiatric illness, religiosity and social support on the degree of suicidal behavior in such group of patients. 150 suicidal patients from the psychiatric outpatient clinic were assessed by Tool for Assessment of Suicide Risk (TASR) for the degree of suicidality, whether high, moderate or low. Rosenberg’s self-esteem scale to assess self-esteem; dealing with illness coping inventory to assess various coping methods and strategies; Religious Orientation scale to assess extrinsic and intrinsic religiosity and Norbeck’s social support questionnaire (NSSQ) to assess the level of social support. Lower self-esteem was associated with higher risk of suicidality and also lower social support carried the same burden. Lower intrinsic religiosity was associated with the highest suicide risk among both Muslims and Christians. The most frequent used coping method was the active cognitive coping and the most used coping strategy was cognitive positive understanding and creates meaning which is a subtype of active cognitive coping. The findings from this large, diverse sample had clinical implications for prevention of suicide and management of high risk patients through increasing their self-esteem, coping skills, spirituality, intrinsic religiosity and faith. Also minimizing the stigma of suicide and mental illness allows for better social and community support for patients.