Malnutrition in HD patients is common the predialysis s. albumin and s. cholesterol are useful screening tools for detecting malnutriton, This study assesses the relation of serum albumin and serum cholesterol as indicators of nutritional status to parameters of iron metabolism in one hundred HD patients and concludes that : Serum albumin level tends to be normal in MHD patients with CRP –ve, There is a positive correlation between serum albumin and hemoglobin in MHD patients and recommends that in absence of inflammatory signs, serum albumin and serum cholesterol should not be relied upon in interpretation of anemia and iron parameters in patients on MHD.