Traditional I-section plate girders are greatly affected by the local buckling of the web when subjected mainly to cyclic loadings inducing shear forces. Additionally, the local buckling can result in a distortion of the flange under compressive forces since an I-section has relatively low torsional stiffness because it is considered as an open section. Therefore, the flat flanges of an I-section plate girder can be replaced with tubular ones thus transforming it into a hollow tubular flange plate girder (HTFPG) which has an enhanced local buckling resistance and torsional stiffness. In this paper, a numerical study is conducted to evaluate the shear performance of HTFPGs subjected to cyclic loading. A three-dimensional finite element (FE) model is built using ANSYS Workbench 2020 R1 software in order to simulate the HTFPGs response. The proposed FE model includes an initial geometric imperfection as well as both material and geometric nonlinearities. A parametric study is carried out on 4 simply supported HTFPGs regarding the web thickness and the aspect ratio. Shear strength, mode of failure, ductility and dissipated energy of the HTFPGs are carried out from the current FE models and then compared to each other. Moreover, a comparison between the HTFPG cyclic and monotonic response is made. Finally, the results demonstrated that hollow flanges can efficiently boost up the shear carrying capacity of the HTFPG. Also, there is no much difference observed between the cyclic and the monotonic shear response of the HTFPGs.