Detection of structures damage has lately received significant attention from the viewpoint of maintenance and safety estimation. There are several types of mechanisms for damage simulation according to the study purpose. Young's modulus was chosen as a damage indicator, in many existing damage detection methods, which worked well for truss elements. By modifying the Young's modulus in element, all DOF's stiffness properties are reduced by the same ratio. However, for column elements, it may be inappropriate to choose Young's modulus as a damage indicator, because damage indicators need to characterize separately the changes of axial and bending stiffness at local level. The proposed approach introduces a real insight for section damage simulation, which accomplished as a reduction in both cross sectional area and inertia of the section, with different damage indicators. Also it estimates the location and severity of the damaged element through an iterative damage detection method. The effectiveness of the proposed method is verified by numerical analysis using a plane frame models. The determination of prioritized sensor locations is performed using Effective Independence method (EFI). Results show the good efficiency of this method to detect single nd multiple daamage scenarios in structure using noisy data.